• Cet ouvrage couvre un programme complet de statistique pour la licence de psychologie (L1 à L3), depuis les bases élémentaires de combinatoire et de probabilités jusqu'aux modèles élaborés permettant de mettre à l'épreuve des hypothèses psychologiques.

    Présentés à partir de données réelles, les modèles étudiés sont facilement applicables dans les champs divers de la psychologie (cognition, cognition sociale, développement de l'enfant, psychologie de la santé, psychologie du travail, psychocriminologie...). La mise en oeuvre pratique des procédures est développée dans des exercices types présentés en un format unique, de la définition du problème statistique à la conclusion psychologique.

    La démarche adoptée par l'auteur est celle de la comparaison de modèles. Chaque situation à modéliser fait d'abord l'objet d'hypothèses psychologiques, traduites sous forme de modèles, parmi lesquels on cherche le meilleur en termes de qualité d'ajustement et de parcimonie. Cette démarche de sélection de modèles est illustrée aussi bien avec les outils fishériens traditionnels (la valeur p), qu'avec les outils les plus récents de la statistique bayésienne (le facteur de Bayes). Les dernières recommandations de l'American Psychological Association en matière d'analyse, notamment l'inférence directe sur les tailles d'effet, ont été intégrées. A ce titre, l'ouvrage intéressera autant l'étudiant que le chercheur désireux de s'initier à ces nouveaux outils.

  • Many readers will doubtless be astonished to learn that animals were being fired aloft in U.S. and Soviet research rockets in the late 1940s. In fact most people not only believe that the Russian space dog Laika was the first canine to be launched into space, but also that the high-profile, precursory Mercury flights of chimps Ham and Enos were the only primate flights conducted by the United States. In fact, both countries had sent literally dozens of animals aloft for many years prior to these events and continued to do so for many years after. Other latter-day space nations, such as France and China, would also begin to use animals in their own space research.
    Animals in Space will explain why dogs, primates, mice and other rodents were chosen and tested, at a time when dedicated scientists from both space nations were determined to establish the survivability of human subjects on both ballistic and orbital space flights. It will also recount the way this happened; the secrecy involved and the methods employed, and offer an objective analysis of how the role of animals as spaceflight test subjects not only evolved, but subsequently changed over the years in response to a public outcry led by animal activists. It will explore the ways in which animal high-altitude and space flight research impacted on space flight biomedicine and technology, and how the results - both successful and disappointing - allowed human beings to then undertake that same hazardous journey with far greater understanding and confidence.
    This book is intended as a detailed yet highly readable and balanced account of the history of animal space flights, and the resultant application of hard-won research to space technology and astrobiology.  It will undoubtedly become the ultimate authority on animal space flights.

  • The package of Gromov's pseudo-holomorphic curves is a major tool in global symplectic geometry and its applications, including mirror symmetry and Hamiltonian dynamics. The Kuranishi structure was introduced by two of the authors of the present volume in the mid-1990s to apply this machinery on general symplectic manifolds without assuming any specific restrictions. It was further amplified by this book's authors in their monograph Lagrangian Intersection Floer Theory and in many other publications of theirs and others. Answering popular demand, the authors now present the current book, in which they provide a detailed, self-contained explanation of the theory of Kuranishi structures.
    Part I discusses the theory on a single space equipped with Kuranishi structure, called a K-space, and its relevant basic package. First, the definition of a K-space and maps to the standard manifold are provided. Definitions are given for fiber products, differential forms, partitions of unity, and the notion of CF-perturbations on the K-space. Then, using CF-perturbations, the authors define the integration on K-space and the push-forward of differential forms, and generalize Stokes' formula and Fubini's theorem in this framework. Also, "virtual fundamental class" is defined, and its cobordism invariance is proved.
    Part II discusses the (compatible) system of K-spaces and the process of going from "geometry" to "homological algebra". Thorough explanations of the extension of given perturbations on the boundary to the interior are presented. Also explained is the process of taking the "homotopy limit" needed to handle a system of infinitely many moduli spaces. Having in mind the future application of these chain level constructions beyond those already known, an axiomatic approach is taken by listing the properties of the system of the relevant moduli spaces and then a self-contained account of the construction of the associated algebraic structures is given. This axiomatic approach makes the exposition contained here independent of previously published construction of relevant structures. 

  • This monograph focuses on the mathematical and numerical analysis of simplicial partitions and the finite element method. This active area of research has become an essential part of physics and engineering, for example in the study of problems involving heat conduction, linear elasticity, semiconductors, Maxwell's equations, Einstein's equations and magnetic and gravitational fields.
    These problems require the simulation of various phenomena and physical fields over complicated structures in three (and higher) dimensions. Since not all structures can be decomposed into simpler objects like d-dimensional rectangular blocks, simplicial partitions are important. In this book an emphasis is placed on angle conditions guaranteeing the convergence of the finite element method for elliptic PDEs with given boundary conditions. 
    It is aimed at a general mathematical audience who is assumed to be familiar with only a few basic results from linear algebra, geometry, and mathematical and numerical analysis. 

  • This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and
    its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.

  • Environmental chemistry is a fast developing science aimed at deciphering fundamental mechanisms ruling the behaviour of pollutants in ecosystems. Applying this knowledge to current environmental issues leads to the remediation of environmental media, and to new, low energy, low emission, sustainable processes. Chapters review analysis and remediation of pollutants such as greenhouse gases, chiral pharmaceuticals, dyes, chlorinated organics, arsenic, toxic metals and pathogen in air, water, plant and soil. Several highlights include the overlooked impact of air pollutants from buildings for health risk, innovative remediation techniques such as bioreactors for gas treatment, electrochemical cleaning of pharmaceuticals, sequestration on Fe-Mn nodules, phytoremediation and photocatalytical inactivation of microbial pathogens. This book will be a valuable source of information for engineers and students developing novel applied techniques to monitor and clean pollutants in air, wastewater, soils and sediments. 

  • This book expands on the classical statistical multivariate analysis theory by focusing on bilinear regression models, a class of models comprising the classical growth curve model and its extensions. In order to analyze the bilinear regression models in an interpretable way, concepts from linear models are extended and applied to tensor spaces. Further, the book considers decompositions of tensor products into natural subspaces, and addresses maximum likelihood estimation, residual analysis, influential observation analysis and testing hypotheses, where properties of estimators such as moments, asymptotic distributions or approximations of distributions are also studied. Throughout the text, examples and several analyzed data sets illustrate the different approaches, and fresh insights into classical multivariate analysis are provided. This monograph is of interest to researchers and Ph.D. students in mathematical statistics, signal processing and other fields where statistical multivariate analysis is utilized. It can also be used as a text for second graduate-level courses on multivariate analysis.

  • This timely book allows clinicians of the nervous system, who are increasingly confronted with degenerative and psychiatric diseases, to familiarize themselves with the cerebral amygdala and the anatomical structures involved in these pathologies. Its striking photos of cerebral sections and dissections should help MRI specialists to more precisely study the detailed images provided by their constantly evolving equipment.

  • This eagerly awaited book offers a unique, comprehensive scientific study of the anatomy of the organ of female sexual pleasure. The authors use macroscopic and microscopic research to guide the reader from the glans, the visible part of the clitoris, where they explore the impressive sensory corpuscles, to the hidden roots of the bulbo-clitoral organ. They show its complexity, its exact location within the external genitalia and its intimate relationship with the urethro-vaginal pyramid.They also remind us that throughout history there has been a failure to understand this organ and explain that this misunderstanding remains the cause of persistent excisions, criminal mutilating practices that have not yet been eradicated.Using extensive iconography, they demonstrate throughout this book that the bulbo-clitoral organ is an exceptional natural treasure that every woman possesses and that every man should know well.

  • Forewords by Claes-Göran Granqvist, Uppsala University, Sweden, and Neal F. Lane, Rice University, TexasNanomaterials inevitably have bright prospects, but even now they play an important role in many areas of industry. Some of these new materials are commercially available and are used in off the shelf products, others are important model systems for physicochemical and materials science research. However, research findings and application data are not compiled in a single work. The Springer Handbook of Nanomaterials collects description and data of materials which have dimensions on the nanoscale. The description of nanomaterials follows the interplay of structure, properties, processing and applications mainly in their solid phase. The chapters were arranged according to the classical materials-science classifications: carbon materials, metals, ceramics, composites, and biomaterials. For each part, materials structures represent different dimensionality; zero-dimensional clusters, nanoparticles and quantum dots, one-dimensional nanowires and nanotubes, and two-dimensional thin films and surfaces. Combinations cover for instance nanostructured and hybrid materials. Almost 100 leading scientists from academia and the industry were selected to write the 32 chapters and collect the physical, chemical and mechanical data. The handbook was written and compiled for professionals and practitioners, materials scientists, physicists and chemists at universities, as well as in the fields of industrial research and production.The Handbook is organized in seven parts. Part A: NanoCarbons. Part B: NanoMetals. Part C: NanoCeramics. Part D: NanoComposits. Part E: Nanoporous Materials. Part F: Organic and Biomaterilas. Part G: Applications and Impact.  

  • Ocular infections remain an important cause of ocular morbidity and loss of vision, yet many are preventable or curable. Early diagnosis and prompt treatment help in the control of such infectious disorders and the prevention of blindness. There are many infectious diseases of the eye and adnexa and knowledge of their diagnosis and management is essential to an optimal therapeutic outcome.This book provides the practitioner with the important information required to ensure appropriate diagnosis and management of ocular infectious diseases. Specific clinical signs and symptoms are outlined, and the role of specific diagnostic tests, including molecular biology techniques, is explained. All of the most common microorganisms are considered and current knowledge on the antimicrobial therapy of ocular infections is clearly summarized. Ocular Infections will be a great help to physicians as a guide to the care of patients with ocular infectious diseases.

  • Faut-il lever l'anonymat du don de sperme ? La question se pose d'autant que plusieurs pays ont modifié leur législation en ce sens et que des enfants devenus adultes revendiquent avec force la possibilité de connaître l'identité de l'homme qui, en donnant son sperme, a permis à leurs parents de les concevoir. Malheureusement le débat reste souvent dans les registres émotionnel et compassionnel, sans réelle évaluation des programmes d'aide à la procréation par don de spermatozoïdes et sans véritable réflexion sur les enjeux et les conséquences des choix éthiques qui devront être faits. Cet ouvrage rend compte du vécu et du regard des équipes médicales et des psychologues qui aident les hommes et les femmes à devenir parents grâce à un don, et donne la parole à des philosophes et à différents spécialistes dans une approche transdisciplinaire. Enfin et surtout, les acteurs eux-mêmes sont présents, qu'ils soient parents, donneurs ou enfants, grâce à leurs très nombreux témoignages.

  • L'endocrinologie pédiatrique est une spécialité large, pratiquée par de nombreux médecins car elle est située à l'interface entre les pathologies d'origine hormonale et les spécificités liées à l'enfance.
    Les Fiches Pratiques d'Endocrinologie Pédiatrique font la synthèse des principaux ouvrages de référence en endocrinologie et en pédiatrie et forment ainsi un des premiers livres en langue française d'endocrinologie pédiatrique. Ce recueil fourni une somme unique d'informations exhaustives sur l'ensemble des pathologies rencontrées en pratique courante d'endocrinologie pédiatrique ; de la croissance aux pathologies surrénaliennes, en passant par la gynéco-pédiatrie et les pathologies pubertaires, il traite également les dysthyroïdies, les pathologies hypothalamo-hypophysaires ou syndromiques, le diabète, les dyslipidémies etc., avec un chapitre complet sur la biologie hormonale et les tests endocriniens adaptés à l'enfant. C'est un guide pratique et didactique, divisé en parties clairement identifiées, avec un index fourni, présenté sous forme de fiches qui détaillent les signes cliniques et bilans paracliniques permettant d'amener au diagnostic, mais aussi la conduite à tenir et la prise en charge thérapeutique adaptées à chaque pathologie. Il pourra être abordé soit à partir d'un signe clinique ou symptôme, soit à partir d'une pathologie connue et diagnostiquée. Outil de formation des internes et des jeunes chefs de clinique, c'est aussi un ouvrage de référence pour les médecins pratiquant l'endocrinologie pédiatrique de façon occasionnelle ou plus régulière, qu'ils soient pédiatres, endocrinologues, médecins de PMI ou médecins généralistes. De petit format et facile d'utilisation, il trouvera sa place dans la poche d'une blouse ou sur le bureau d'un cabinet médical. Un guide pratique et didactique, de petit format et facile d'utilisation. Un outil de formation des internes et des jeunes chefs de clinique. Un ouvrage de référence pour les médecins pratiquant l'endocrinologie pédiatrique de façon occasionnelle ou plus régulière, qu'ils soient pédiatres, endocrinologues, médecins de PMI ou médecins généralistes.

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  • Les mécanismes physiopathologiques impliqués chez les patients de réanimation accordent une place prépondérante aux modifications métaboliques. Initiées au niveau élémentaire cellulaire, ces anomalies prennent tout leur sens dans une vision intégrée élargie d'organe et globale pour l'ensemble de l'organisme. Le diagnostic et le traitement des troubles métaboliques aigus observés chez les patients de réanimation imposent une démarche physiopathologique. Les chapitres abordés dans ce livre incluent la prise en charge des principaux troubles hydroélectrolytiques, de l'équilibre acide-base, ainsi que des anomalies métaboliques impliquées dans les défaillances rénales, cérébrales et hépatiques. D'autres chapitres sont consacrés aux anomalies endocriniennes aiguës observées en réanimation, qu'il s'agisse de l'insuffisance surrénalienne, de l'hyperglycémie de stress ou des complications métaboliques aiguës du patient diabétique. La dernière partie de l'ouvrage est consacrée aux notions modernes de nutrition en réanimation et aux modifications du métabolisme énergétique qui incluent les dysfonctionnements mitochondriaux, les phénomènes d'ischémie-reperfusion et le stress oxydant ouvrant la voie à de nouveaux espoirs thérapeutiques.

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  • A la fin des années 90, les soins de développement étaient classés lors d'un congrès médical américain dans le « Top-ten » des thérapeutiques inutiles. Près de 15 ans plus tard, les soins de développement sont utilisés à des degrés divers par la quasi-totalité des équipes de néonatalogie. Les données de la recherche clinique accumulées durant la dernière décennie ont considérablement enrichi notre savoir et permis ainsi de modifier les pratiques. Cette recherche concerne différents champs scientifiques : les neurosciences, la psychologie clinique et développementale, les sciences infirmières et médicales... et alimente le débat, forcément international. Les questions techniques se doublent d'une réflexion éthique : quelle philosophie de soins dans le monde de la périnatalité de demain ? Les associations de parents, nationales ou européennes, jouent désormais un rôle important au côté des professionnels dans la conduite de cette réflexion. Cet ouvrage, rédigé par de nombreux experts francophones, se veut un pont entre les données de la recherche et les pratiques de terrain. Visant à réduire l'incertitude scientifique, il dresse l'état des connaissances actuelles, propose des stratégies de terrain et souligne les domaines restant à explorer. Il s'adresse aux nombreux professionnels de la périnatalité : pédiatres, infirmières et puéricultrices, sage-femmes, psychologues, psychomotriciens, kinésithérapeutes, chercheurs et épidémiologistes.

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  • This book presents the latest information on tropical tree physiology, making it a valuable research tool for a wide variety of researchers. It is also of general interest to ecologists (e.g. Ecological Society of America; > 3000 or 4000 members at annual meeting), physiologists (e.g. American Society of Plant Biologists; > 2,000 members at annual meeting), and tropical biologists (e.g. Association for Tropical Biology and Conservation, ATBC; > 500 members at annual meeting). (American Geophysical Union(AGU), > 20000 members at annual meeting). Since plant physiology is taught at every university that offers a life sciences, forestry or agricultural program, and physiology is a focus at research institutes and agencies worldwide, the book is a must-have for university and research institution libraries.

  • The purpose of this textbook is to enable a Neuroscientist to discuss the structure and functions of the brain at a level appropriate for students at many levels of study including undergraduate, graduate, dental or medical school level. It is truer in neurology than in any other system of medicine that a firm knowledge of basic science material, that is, the anatomy, physiology and pathology of the nervous system, enables one to readily arrive at the diagnosis of where the disease process is located and to apply their knowledge at solving problems in clinical situations. The authors have a long experience in teaching neuroscience courses at the first or second year level to medical and dental students and to residents in which clinical information and clinical problem solving are integral to the course.